Navigating the Current Landscape of Non-Clear Cell Renal Cell Carcinoma: A Review of the Literature

Navigating the Current Landscape of Non-Clear Cell Renal Cell Carcinoma: A Review of the Literature

Blog Article

Non-clear cell renal cell carcinoma (nccRCC) is an entity comprised of a heterogeneous constellation of RCC subtypes.Genomic profiling has broadened our understanding of 15-eg2373cl molecular pathogenic mechanisms unique to individual nccRCC subtypes.To date, clinical trials evaluating the use of immunotherapies and targeted therapies have predominantly been conducted in patients with clear cell histology.

A comprehensive review of the literature has been undertaken in order to describe molecular pathogenic mechanisms pertaining to each 12n/1200 wella nccRCC subtype, and concisely summarise findings from therapeutic trials conducted in the nccRCC space.